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SETTLE & SOOTHE

SETTLE & SOOTHE

histamine relief

Regular price $64
Regular price $64 Sale price $64
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a collaboration with The Holistic Mother

This unique blend offers swift relief for seasonal allergies, stabilizes mast cells, and reduces histamine response.

This blend can help:

  • those with MCAS and/or histamine intolerance
  • those who have systematic symptoms of increased histamine like anxiety, GI issues & headaches
  • those who deal with anxiety
  • helps decrease microglia activation and rage
  • those with seasonal allergies
  • decrease ammonia and inhibit glutamate (great for kids with autism who flare due to histamine)

Pair it with THE LIVER PROTECTOR for allergy relief as many allergy and asthma symptoms are connected to liver health.

Mast Cell & Histamine Balance

A powerful yet gentle formula designed to calm histamine responses, stabilize mast cells, and support whole-body balance. Settle & Soothe is crafted for those with histamine intolerance, MCAS, seasonal allergies, and nervous system dysregulation—helping to ease inflammation, reduce reactivity, and promote a state of calm.

Supports Histamine & Nervous System Regulation
  • Reduces Histamine Response – Helps regulate histamine levels, reducing symptoms like flushing, headaches, and digestive discomfort.
  • Stabilizes Mast Cells – Supports immune balance for those with MCAS or histamine-driven sensitivities.
  • Calms the Nervous System – Helps ease anxiety, microglial activation, and nervous system overstimulation.
  • Eases Seasonal Allergies – Naturally supports respiratory health and immune resilience.
Key Ingredients for Mast Cell Stability & Nervous System Support
  • Chinese Skullcap Root – A well-studied mast cell stabilizer known to support histamine balance and immune regulation.
  • Nettle Leaf – Naturally supports respiratory function and histamine metabolism, reducing allergy symptoms.
  • Albizia Bark Extract – Traditionally used for emotional regulation and calming excessive immune responses.
  • Holy Basil – Adaptogenic herb that reduces stress-driven histamine release and supports nervous system balance.
  • Perilla Leaf Extract – Shown to support histamine metabolism and gut health, helping reduce food-related histamine reactions.
  • Goldenrod & Calendula – Herbal allies for reducing inflammation and soothing hypersensitive immune responses.
  • Giloy (Guduchi) Leaf & Stem – An Ayurvedic powerhouse for immune modulation, helping to restore equilibrium in overactive immune systems.
Who Is This Best For?
  • Those with MCAS or histamine intolerance needing natural histamine regulation.
  • Individuals experiencing systemic histamine symptoms like anxiety, GI issues, and headaches.
  • Those prone to seasonal allergies and respiratory sensitivities.
  • Individuals with neuroinflammation, including those with microglial overactivation, rage episodes, or histamine-related anxiety.
  • Kids with autism spectrum-related histamine flares, ammonia buildup, or glutamate sensitivity.
A Daily Ally for Histamine & Immune Balance

Unlike conventional antihistamines that suppress symptoms, Settle & Soothe works with the body to restore balance naturally.

Calm your system, ease reactivity, and restore harmony—without suppression.

· highly concentrated
· approx 800mg/ml herbal propriety blend
· dual extraction
· alcohol-free
· organic coconut glycerin-based

· Organic Chinese Skullcap Root
· Organic Nettle Leaf
· Organic Albizia Bark Extract
· Organic Holy Basil Leaf
· Organic Perilla Leaf Extract
· Organic Calendula Flower
· Organic Goldenrod Leaf & Stem
· Organic Giloy Leaf & Stem

other ingredients:
Organic Coconut Glycerin, Purified Water

Adults: Take 10 drops (approx. ½ dropper) up to 3 times a day or as directed by your healthcare provider.

Children: Take 1 drop per 10 lbs of body weight up to 3 times a day or as directed by your healthcare provider.
Can be taken directly on the tongue or mixed with water or tea. Shake well before use.

Finding Your Optimal Dose:
This is a standard suggested dosage, but everyone’s body is different. Factors like individual biochemistry, health concerns, and current symptoms may mean that some people need less—while others may benefit from a higher or more frequent dose.

During times of illness or increased stress, you may find that a higher or more frequent dose is needed for optimal support. Start with a smaller dose, listen to your body, and adjust accordingly.

As always, consult with your healthcare provider before beginning a new supplement.

do not take while pregnant. safe to use while breastfeeding however, always consult your doctor before use.

Wild Wholistic blends are premium, pure, highly concentrated, and very potent. This makes it critically important to start implementing our blends slowly into your daily diet. Go low and slow. Start with a minimal dose every day or every other day. Listen to your body intuitively and slowly build up the dosage in the coming days or weeks to the suggested dosage or the dosage that most resonates with you and works best for your body.

DISCLAIMER****WILD WHOLISTIC is not responsible for individual misuse of herbs or any possible sensitivities or reactions. It is the customer's responsibility to know the individual herbal frequency, recommendations, cautions, interactions, toxicities, sensitivities, reactions, and individual health issues before using herbs and any Wild Wholistic blends.

It is the individual responsibility to always check the ingredients of the blend and/or check with their doctor before making a purchase to make sure they are not sensitive to any ingredients listed or the mixture doesn't interact with medications or supplements they currently take.

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Wild Wholistic has quietly set the gold standard since the very beginning—without hype, without false claims, and always ahead of the curve. We don’t chase trends. We define the future of wellness with unmatched purity, potency, and integrity.
Wild Wholistic:
Quietly setting the standard since the beginning—no false claims, just unmatched purity, potency, and integrity.
Absolutely No Industrial Seed Oil Glycerins

purity you can trust—from the inside out.

Most vegetable glycerin-based supplements rely on cheap industrial seed oils like soybean, canola, grape seed, sunflower, or safflower. These oils are often highly processed and can produce lipid peroxides and free radicals, contributing to oxidative stress and inflammation.

Regular exposure has been linked to chronic inflammation, hormonal imbalance, gut irritation, and accelerated aging.

Wild Wholistic has pioneered the use of organic coconut glycerin—a pure, stable, and superior alternative that honors both the body and the plants.

✓ Made with organic coconut glycerin
✓ Zero industrial seed oil byproducts
✓ Free from inflammatory lipids

Our Commitment: No shortcuts, no compromises—just clean, uncompromised extraction.

Ultra-Concentrated & Double-Extracted

designed for deep impact, not just daily routine.

Every Wild Wholistic blend is crafted at herbal ratios far beyond standard tinctures. Using advanced spagyric or dual-solvent extraction methods, we capture both water-soluble and fat-soluble constituents for full-spectrum potency.

Most products on the market are diluted. Ours are therapeutic-grade—trusted by practitioners and customers who feel the difference.

✓ Spagyric and dual-extraction techniques
✓ Therapeutic herbal ratios, never diluted
✓ Practitioner-trusted and clinically inspired

Our Commitment: Every drop is intentional. Every dose, deeply effective.

Ultra-Concentrated & Double-Extracted

designed for deep impact, not just daily routine.

Every Wild Wholistic blend is crafted at herbal ratios far beyond standard tinctures. Using advanced spagyric or dual-solvent extraction methods, we capture both water-soluble and fat-soluble constituents for full-spectrum potency.

Most products on the market are diluted. Ours are therapeutic-grade—trusted by practitioners and customers who feel the difference.

✓ Spagyric and dual-extraction techniques
✓ Therapeutic herbal ratios, never diluted
✓ Practitioner-trusted and clinically inspired

Our Commitment: Every drop is intentional. Every dose, deeply effective.

Organic, Wildcrafted & Third-Party Tested

where ancient plants meet modern integrity.

We source only organic and wildcrafted herbs—never conventionally farmed, irradiated, or chemically extracted. Each ingredient is independently tested for purity, heavy metals, and microbial safety. Every batch is verified for consistency and quality.

Transparency isn’t just a promise—it’s our protocol.

✓ Certified organic and wildcrafted herbs
✓ Third-party testing on every ingredient and batch
✓ Zero irradiation, fillers, or chemical solvents

Our Commitment: Radical transparency. Verified excellence.

    Customer Reviews

    Based on 73 reviews
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    A
    Andrea
    Amazing Product

    This helps instantly for anyone who deals with allergies or a high histamine response. I always keep this on hand and have recommended to countless people!

    B
    Bethany W.
    Truly Works

    This product is truly amazing- my daughter has eczema and it is absolutely helping her histamine responds to irritants. It is gentle and easy to give to a baby! So very pleased.

    B
    Brooke M.
    Great Histamine Support

    We love this product in our house! Just started it at the beginning of pollen season and I hardly have any seasonal allergy symptoms that I usually do. Also helps with other histamine responses to high histamine foods and other histamine triggers.

    C
    Chrissy S.
    Histamine Support

    Settle & Soothe has been a game-changer for my histamine issues! I would recommend it to anyone!

    N
    Nes
    For anxiety and chronic rhinitis

    In started the combination of Settle and Soothe and Liver Protection for the episode of dermatitis I’ve been fighting for almost a year. And although it didn’t help, I did experienced way less anxiety and the ceased of allergic rhinitis. Surprisingly, I spent Christmas without allergies. Everyone was sick, except me. It’s been a little over a week without the tinctures, and the allergies came back.